| You can modify your settings by the following 1.) write to: CO Cohen & Verrel Data Solutions [7462 Heaton Circle Maineville OH 45039) go/here http://www.alsa.org/news/archive/advances-in-als-and-ftd-workshop.html The ice bucket challenge for ALS is a and it's good On November 14, 2014, The ALS Association, the [num1] Institute of Neurological Disorders and Stroke (NINDS) and the Association for Frontotemporal [num1] (AFTD) will lead a workshop on advances in ALS and FTD [num1] Next-generation [num1] techniques have [num1] as a powerful approach to address knowledge gaps in the genetic etiology of complex neurodegenerative [num1]. Accordingly, efforts are underway to sequence a [num1] number of human exomes and whole genomes to identify rare variants that could increase the risk for or modify the onset, [num1] or [num1] of neurodegenerative [num1]. In amyotrophic lateral sclerosis (ALS) and frontotemporal [num1] (FTD), two disorders with genetic and pathological overlap, recent gene discoveries are transforming our understanding of disease biology. The [num1] of the C9orf72 hexanucleotide repeat expansion, for instance, now defines a spectrum [num1] termed FTD-ALS, where the same [num1] can cause either motor or [num1] onset and in rare cases both. [num1], a significant [num1] of familial ALS and FTD, and most of the [num1] forms of these diseases, remain unexplained. Multiple large-scale [num1] efforts are underway to identify missing disease mutations. These [num1] are being [num1] by multiple genetics consortia [num1] by private and/or public sources. This symposium will [num1] a forum for these [num1] to provide status updates, discuss opportunities to coordinate efforts, build consensus on [num1] data elements, facilitate data sharing across different platforms, and identify remaining gaps and next steps. No, I havent poured a bucket of ice water over my head and posted an online video of myself doing so on my social media accounts for you all to scrutinize. |
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