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The Directorate of Biological Sciences (BIO) is notifying members of the research community of important changes to the core program solicitations effective in calendar year 2018.You are strongly encouraged to read theDear Colleague Letterand theFrequently Asked Questionsfor complete details and contact your program officer for specific questions. In order to promote interdisciplinary research that crosses biological scales and traverses current divisional boundaries, BIO will implement a “no-deadline”, full-proposal mechanism for receiving and reviewing proposals submitted to core programs in theDivision of Environmental Biology (DEB), the Division of Integrative Organismal Systems (IOS), the Division of Molecular and Cellular Biosciences (MCB), and to the programs in the Research Resources Cluster of the Division of Biological Infrastructure (DBI).